Program

Monday, March 26th, 2018

10:30 – 11:00 h

Welcome coffee / Registration

11:00 – 11:15 h

Welcome address Stefan Schreiber

11:15 – 12:25 h

Session I — Genomic Diversity of CIBD

Chair: Wolfgang Lieb, Kiel University

11:15 – 11:35 h

Jeanette Erdmann: Update on CAD genetics - from single families to large-scale GWAS

11:35 – 12:00 h

Jan Freudenberg, Regeneron Genetics Center, Tarrytown, US: Large-scale exome sequencing for inflammatory diseases – Opportunities and challenges for drug discovery

12:00 – 12:25 h

Kenneth Croitoru, University of Toronto, CA: Study design and first results of the GEM cohort for IBD

12:30 – 13:30 h

Lunch

13:30 – 14:40 h

Session II — Evolution and Ecology of Microbiomes

Chair: Hinrich Schulenburg, Kiel University

13:30 – 13:50 h

Stefan Niemann: Evolution and transmission of multidrug resistant M. tuberculosis strains

13:50 – 14:15 h

Sébastien Gagneux, SwissTPH, Basel, CH: Genome evolution of Mycobacterium tuberculosis

14:15 – 14:40 h

Craig Winstanley, University of Liverpool, UK: The evolution of Pseudomonas aeruginosa populations in the Cystic Fibrosis lung

14:45 – 15:55 h

Session III — Individualized Cellular Models and Epigenetic Signatures of Inflammation

Chair: Franz-Josef Müller, Kiel University

14:45 – 15:05 h

Philip Rosenstiel: Intestinal epithelial cells - epigenetic signatures, microbiota, and intestinal inflammation

15:05 – 15:30 h

Henk Stunnenberg, Radbound University, Nijmegen, NL: Epigenetic marks, immunity and human disease

15:30 – 15:55 h

Mamoru Watanabe, Tokyo University Hospital, JP: Organoids as a therapy resource – from clinical trail in a dish to engraftment

16:00 – 16:30 h

Coffee Break

16:30 – 17:40 h

Session IV — Clinical and Nutritional Metabolomics

Chair: Karin Schwarz, Kiel University

16:30 – 16:50 h

Matthias Laudes: Metabolic Inflammation - a potential novel treatment target for CIBD

16:50 – 17:15 h

Cédric Laczny, LCSB, Luxembourg, LU: Systems Ecology of the Human Gut Microbiome in Health and Disease

17:15 – 17:40 h

Anthony Whetton, University of Manchester, UK: Protein Biomakers for Precision Medicine

17:45 – 18:55 h

Session V — Experimental Models of Inflammation

Chair: Jörg Köhl, University of Lübeck

17:45 – 18:05 h

Ralf Ludwig, University of Lübeck, DE: Individualized mouse models

18:05 – 18:30 h

Taeko Noah, Cincinnati Children’s Hospital, US: Intestinal Epithelial Allergen Sampling and Food Allergy

18:30 – 18:55 h

Ralf Baumeister, University of Freiburg, DE: C. elegans models of signaling: Pathways, targets, drugs

19:00 – 19:45 h

Key Note Lecture

Chair: Stefan Schreiber, Kiel University

Friedrich von Bohlen und Halbach, dievini, Walldorf, DE: Precision Medicine in Healthcare and Drug Development

20:00 – 23:00 h

Poster Session / Buffet

Tuesday, March 27th, 2018

08:15 – 09:25 h

Session VI — Sequence-based Profiling

Chair: Frank Kaiser, University of Lübeck

08:15 – 08:35 h

Andre Franke: 5 Years in a Nutshell: Nucleotide Lab Evolution to a Comprehensive Center for Genome Analysis

08:35 – 09:00 h

Ivo Gut, University of Barcelona, ES: Multi-omics and human diseases

09:00 – 09:25 h

Ann-Christine Syvänen, Uppsala University, SE: Genomic analyses of systemic lupus erythematosus (SLE)

09:30 – 10:45 h

Session VII — Multiscale Imaging

Chair: Magdalena Rafecas, University of Lübeck

09:30 – 09:50 h

Robert Huber: New Horizons of imaging technology for inflammation

09:50 – 10:15 h

Uwe Himmelreich, KU Leuven, BE: In vivo Molecular Imaging of Inflammation

10:15 – 10:45 h

Jürgen Popp, Leibniz-IPHT, Jena, DE: Modern Optics in Medicine

10:45 – 11:00 h

Poster Award Presentation

11:00 – 11:30 h

Coffee break

11:30 – 12:40 h

Session VIII — Theoretical Models of Inflammation

Chair: Hauke Busch, University of Lübeck

11:30 – 11:50 h

Christoph Kaleta: Model-based approaches for designing personalized therapies in inflammation medicine

11:50 – 12:15 h

Robert Beardmore, University of Exeter, UK: Antibiotic resistance evolution: different dosages maximise selection for different resistance mechanisms (a case study with erythromycin)

12:15 – 12:40 h

Julio Vera-González, University Erlangen-Nürnberg, DE: The use of systems approaches in the design and personalization of anti cancer immunotherapy

12:45 – 13:30 h

Lunch

13:30 – 14:15 h

Session IX — Ethics, Communication and Economics

Chair: Christoph Rehmann-Sutter, University of Lübeck

13:30 – 13:50 h

Cornelius Borck: Interdisciplinary Research and Translation Problems in Precision Medicine

13:50 – 14:15 h

Ursula Klingmüller, German Cancer Research Center (DKFZ), Heidelberg, DE: Ethics, bio-politics and regulation of precision medicine

14:15 – 14:30 h

Conclusions / Farewell Stefan Schreiber

The program can be downloaded here (pdf).

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